GenPE - Estudio de Genes Candidatos en Preeclampsia

International Alliances PDF Print E-mail
Aroon Hingonani (datos)

Juan Pablo Casas (datos)

United Kingdom members of the GenPE study


The London team composed of Dr Juan P. Casas, (co-principal investigator), and Professors Aroon Hingorani (co-investigator), Liam Smeeth (collaborator) and John Whittaker (collaborator), has great expertise in the area of genetics, statistical epidemiology and cardiovascular medicine.  The team of investigators has also built strong links with UK-based GOPEC study (Dr Linda Morgan and Prof Mark Caulfield). This will allow us to collaborate closely in our work on gene discovery, replication of findings and future works on fetal DNA. The list of international collaborators of the GenPE study also include a wide list of members in different areas of expertise, including Dr Gianpiero Cavalleri expert in population genetics, Dr David Williams expert in Women's health and Prof Pat Doyle expert in reproductive epidemiology.


List of UK-based investigators of the GenPE Study


Dr Juan P. Casas MD, PhD
Co-Principal investigator
Department of Epidemiology and Population Health
London School of Hygiene & Tropical Medicine

Department of Epidemiology and Public Health
University College London

Professor Aroon D. Hingorani, MB, BS, PhD
Genetic Epidemiology Group
Department of Epidemiology and Public Health
University College London

List of collaborators
John Whittaker
Liam Smeeth
David Williams
Gianpiero Cavalleri
Linda Morgan
Mina Savvidou


List of relevant recent publications from the GenPE


  • Bellamy L, Casas JP, Hingorani AD, Williams DJ. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ. 2007 Nov 10;335(7627):974.


  • Serrano NC, Diaz LA, Paez MC, Mesa CM, Cifuentes R, Monterrosa A, Gonzalez A, Smeeth L, Hingorani AD, Casas JP. Angiotensin-converting enzyme I/D polymorphism and preeclampsia risk: evidence of small-study bias. PLoS Med 2006;3: e520
  •  Verzilli C, Shah T, Casas JP, Chapman J, Sandhu M, Debenham SL, Boekholdt SM, Tee Khaw  K, Wareham NJ, Judson R, Benjamin EJ, Kathiresan S, Larson MG, Rong J, Sofat R, Humphries SE, Smeeth L, Cavalleri G, Whittaker JC, Hingorani AD. Bayesian meta-analysis of genetic association studies with different sets of markers. Am J Hum Genet 2008;82(4):859-72.


  • Bellamy L, Casas JP, Hingorani AD, Williams D.  Type 2 diabetes mellitus after gestational diabetes: a systematic review and meta-analysis.  Lancent. 2009 May 23;373(9677):1773-9.








Coordinator Centre


International Alliances

University College London


London School of Hygiene & Tropical Medicine


Buscador GenPE

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